Details for gene set NCI_P75(NTR)-MEDIATED SIGNALING[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB
Phenotype	phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	NCI_P75(NTR)-MEDIATED SIGNALING
Enrichment Score (ES)	-0.64293003
Normalized Enrichment Score (NES)	-1.5495468
Nominal p-value	0.0
FDR q-value	0.1223675
FWER p-Value	0.809

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CCND1	4487 4488 8707 17535	85	2.719	0.0358	No
2	TIAM1	22547	687	1.091	0.0195	No
3	YWHAQ	10369	1061	0.761	0.0106	No
4	CYCS	8821	1112	0.728	0.0187	No
5	MAGEH1	24029	1207	0.670	0.0236	No
6	ARRB2	20806	1303	0.619	0.0277	No
7	IRAK1	4916	1367	0.587	0.0330	No
8	SRF	22961 1597	1447	0.548	0.0368	No
9	MALT1	6274	1542	0.516	0.0394	No
10	YWHAZ	10370	1567	0.504	0.0456	No
11	NFKB2	23810	1631	0.479	0.0493	No
12	FAIM	19344	1717	0.449	0.0514	No
13	IKBKB	4907	1740	0.441	0.0568	No
14	CHUK	23665	1827	0.403	0.0581	No
15	PRKCZ	5260	1997	0.346	0.0541	No
16	YWHAE	20776	2133	0.303	0.0513	No
17	E2F1	14384	2208	0.278	0.0514	No
18	MAPK8	6459	2251	0.267	0.0531	No
19	RPS6KA1	15725	2384	0.231	0.0494	No
20	MYD88	18970	2481	0.202	0.0472	No
21	MAP2K1	19082	2640	0.166	0.0411	No
22	MEF2C	3204 9378	2762	0.145	0.0367	No
23	DIABLO	16375	2875	0.125	0.0325	No
24	APP	4402	2989	0.108	0.0280	No
25	CDK5R1	20745	2995	0.108	0.0293	No
26	CASP3	8693	3119	0.092	0.0240	No
27	PLG	1593 23383	3208	0.082	0.0205	No
28	RTN4	7569 1328 1343 1442	3265	0.076	0.0186	No
29	DNAJA3	1732 13518	3357	0.070	0.0147	No
30	BCL2L11	2790 14861	3579	0.055	0.0035	No
31	ARHGDIA	20116	3705	0.049	-0.0025	No
32	GIPC1	3841 3882 18552	3828	0.044	-0.0085	No
33	RAPGEF1	4218 2860	3945	0.040	-0.0142	No
34	AKT1	8568	4202	0.032	-0.0276	No
35	FOS	21202	4235	0.031	-0.0288	No
36	ABL1	2693 4301 2794	4331	0.029	-0.0335	No
37	SHC1	9813 9812 5430	4437	0.027	-0.0388	No
38	STAT5A	20664	4526	0.025	-0.0432	No
39	NTRK2	9491	4545	0.025	-0.0438	No
40	NTRK3	2069 3652 3705 9492	4552	0.025	-0.0438	No
41	CAMK2A	2024 23541 1980	4715	0.022	-0.0522	No
42	HRAS	4868	4722	0.022	-0.0522	No
43	FRS3	23209	4728	0.022	-0.0522	No
44	NTF3	16991	4821	0.021	-0.0568	No
45	NDN	18222	5204	0.017	-0.0773	No
46	IKBKG	2570 2562 4908	5311	0.016	-0.0828	No
47	RASGRF1	3050 19357	5369	0.015	-0.0857	No
48	MATK	3425 19930	5426	0.015	-0.0885	No
49	SHC3	21465	5554	0.014	-0.0952	No
50	RIPK2	2528 15935	5631	0.013	-0.0991	No
51	APH1A	15501 5947 10378	5915	0.011	-0.1142	No
52	MAG	17880	5926	0.011	-0.1146	No
53	FBXW11	20926	5928	0.011	-0.1145	No
54	BDNF	14926 2797	6229	0.010	-0.1306	No
55	MMP7	19568	6250	0.010	-0.1315	No
56	SRC	5507	6276	0.009	-0.1328	No
57	RHOA	8624 4409 4410	6499	0.009	-0.1447	No
58	RAP1A	8467	7144	0.006	-0.1795	No
59	CDC42	4503 8722 4504 2465	7364	0.005	-0.1912	No
60	RHOC	15467	7450	0.005	-0.1958	No
61	SFN	7060 12062	7743	0.004	-0.2115	No
62	RIT2	5380	8134	0.003	-0.2326	No
63	XPO1	4172	8147	0.003	-0.2332	No
64	MMP3	19572 3148	8689	0.002	-0.2625	No
65	ATM	2976 19115	9162	0.001	-0.2880	No
66	DNM1	2777 8857	9407	0.000	-0.3012	No
67	PRKCI	9576	9472	0.000	-0.3047	No
68	OMG	5209	9691	-0.001	-0.3165	No
69	PLCG1	14753	9774	-0.001	-0.3209	No
70	PSEN1	5297 2125 9630	10258	-0.002	-0.3471	No
71	NRAS	5191	10314	-0.002	-0.3500	No
72	RPS6KA5	2076 21005	10489	-0.002	-0.3594	No
73	RTN4R	22830	10611	-0.003	-0.3659	No
74	YWHAH	5937 10368	10669	-0.003	-0.3690	No
75	SOS1	5476	10751	-0.003	-0.3733	No
76	CAMK4	4473	10887	-0.004	-0.3806	No
77	PIK3R1	3170	11690	-0.006	-0.4239	No
78	NTRK1	15299	12042	-0.007	-0.4428	No
79	PTPN11	5326 16391 9660	12084	-0.007	-0.4449	No
80	CREB1	3990 8782 4558 4093	12093	-0.007	-0.4453	No
81	TRPC3	15355	12642	-0.010	-0.4748	No
82	TNF	23004	12661	-0.010	-0.4756	No
83	NGFR	5174	13147	-0.013	-0.5017	No
84	CASP6	15422 1885	13205	-0.013	-0.5046	No
85	FOXO3	19782 3402	13423	-0.015	-0.5161	No
86	SORT1	15452 5475 9847	13489	-0.016	-0.5194	No
87	MAP3K2	11165	13691	-0.018	-0.5301	No
88	CRK	4559 1249	13772	-0.019	-0.5341	No
89	PIK3CA	9562	13925	-0.021	-0.5420	No
90	GAB2	1821 18184 2025	14144	-0.024	-0.5535	No
91	ERC1	1013 17021 995 1136	14333	-0.027	-0.5633	No
92	MAGED1	24108	14402	-0.029	-0.5665	No
93	MCF2L	18680 5082	14495	-0.030	-0.5711	No
94	RUSC1	1853 15283	14532	-0.031	-0.5725	No
95	MAPK10	11169	14546	-0.032	-0.5728	No
96	MAPK7	1381 20414	15001	-0.047	-0.5967	No
97	TNFRSF1A	1181 10206	15227	-0.057	-0.6080	No
98	NOD2	6384	15341	-0.064	-0.6132	No
99	BCL3	8654	15460	-0.074	-0.6185	No
100	MAP2K5	19088	15507	-0.079	-0.6198	No
101	CASP9	16001 2410 2458	15518	-0.080	-0.6191	No
102	FURIN	9538	15674	-0.093	-0.6261	No
103	YWHAB	14744	15786	-0.105	-0.6306	No
104	NGFRAP1	24246	15886	-0.118	-0.6342	No
105	RGS19	14303	15983	-0.137	-0.6374	No
106	MAP3K14	11998	16026	-0.144	-0.6375	No
107	CDK5	16591	16077	-0.157	-0.6379	No
108	REL	9716	16087	-0.160	-0.6360	No
109	MAP2K3	20856	16216	-0.188	-0.6401	Yes
110	YWHAG	16339	16238	-0.194	-0.6384	Yes
111	RASA1	10174	16249	-0.195	-0.6360	Yes
112	MAPK14	23313	16271	-0.200	-0.6342	Yes
113	NDNL2	17804	16273	-0.200	-0.6313	Yes
114	CYLD	18532	16280	-0.201	-0.6286	Yes
115	BIRC3	19247	16305	-0.207	-0.6268	Yes
116	RELB	17942	16324	-0.211	-0.6247	Yes
117	PRKCD	21897	16416	-0.233	-0.6261	Yes
118	RAF1	17035	16474	-0.248	-0.6255	Yes
119	APAF1	8606	16701	-0.317	-0.6331	Yes
120	UBE2D3	7253	16771	-0.341	-0.6317	Yes
121	ADAM17	4343	16871	-0.384	-0.6314	Yes
122	GRB2	20149	16888	-0.389	-0.6265	Yes
123	SMPD2	5462	16959	-0.418	-0.6240	Yes
124	MAP2K6	20614 1414	16980	-0.426	-0.6188	Yes
125	MAPK3	6458 11170	17011	-0.437	-0.6139	Yes
126	RAC1	16302	17052	-0.451	-0.6094	Yes
127	BIRC2	4397 4398	17138	-0.482	-0.6068	Yes
128	PRKCA	20174	17237	-0.520	-0.6044	Yes
129	GSK3B	22761	17503	-0.658	-0.6089	Yes
130	NCSTN	930 12236	17510	-0.662	-0.5994	Yes
131	SYK	21636	17551	-0.690	-0.5913	Yes
132	RELA	23783	17583	-0.705	-0.5825	Yes
133	BAD	24000	17587	-0.709	-0.5721	Yes
134	NFKB1	15160	17682	-0.778	-0.5657	Yes
135	CRKL	4560	17704	-0.794	-0.5550	Yes
136	RAP1B	10083	17748	-0.823	-0.5451	Yes
137	NEDD4L	8192	17892	-0.942	-0.5388	Yes
138	NFKBIA	21065	18048	-1.142	-0.5302	Yes
139	BCL10	15397	18079	-1.187	-0.5142	Yes
140	PDPK1	23097	18082	-1.189	-0.4966	Yes
141	TRAF6	5797 14940	18100	-1.214	-0.4795	Yes
142	GAB1	18828	18157	-1.275	-0.4636	Yes
143	TNFAIP3	19810	18163	-1.292	-0.4446	Yes
144	RHOB	4411	18166	-1.305	-0.4253	Yes
145	STAT3	5525 9906	18210	-1.378	-0.4072	Yes
146	LCK	15746	18240	-1.451	-0.3872	Yes
147	RIT1	5382	18243	-1.461	-0.3656	Yes
148	EHD4	8275	18265	-1.508	-0.3443	Yes
149	SQSTM1	9517	18281	-1.543	-0.3221	Yes
150	MAPKAPK2	13838	18287	-1.556	-0.2993	Yes
151	KRAS	9247	18298	-1.598	-0.2761	Yes
152	ELMO1	3275 8939 3202 3271 3254 3235 3164 3175 3274 3188 3293 3214 3218 3239	18347	-1.737	-0.2528	Yes
153	MAPK9	1233 20903 1383	18355	-1.758	-0.2271	Yes
154	TP53	20822	18549	-2.941	-0.1938	Yes
155	EGR1	23598	18576	-3.676	-0.1405	Yes
156	MAPK1	1642 11167	18579	-3.793	-0.0842	Yes
157	RAN	5356 9691	18611	-5.795	0.0003	Yes